Nicotine, Vaping & Anxiety: Key Insights Clutch Vape Teens who vape or smoke more likely to experience depression and anxiety, study of over 60,000 u.s. students finds. Youth using both e cigarettes and traditional tobacco report the highest levels of mental If you vape to cope with stress or anxiety, you might be making it worse. Nicotine, a chemical commonly found in vapes and e cigarettes, is addictive and can cause a cycle of dependence. Our Vaping Can Increase Stress, Irritibility, Anxiety, and Mood Swings. CYANOnline Anxiety, Stress, and Vaping Smokefree Teen