15 Best CBD Vape Pens for Anxiety and Relaxation Allure Vaping nicotine can make anxiety, mood swings, and focus worse. Instead of turning to a vape to cope with stress, try one of these healthy ways to feel better. Need help to Do Anxiety Pens Really Work? What to Know Students might vape when anxious or depressed, creating a cycle of nicotine dependence and withdrawal. Understand the risks of youth vaping: cdc.gov e cigarettes VapingAndMentalHealth_Module3